Generated Ref/Alt from variant. -Dels are the ref position + length of deletion with the anchor base (Start - 1) added, the alt is just the anchor. -Insertions are the insert sequence and nothing in ref. -Substitions are split using the sub(Ref->Alt) format. Filtered for proband only Added “.p1” to “quadid” column to be used as new proband sample ID’s. Added validation information/columns. Split PAFAH1B2\x3bPAFAH1B2 on \x3b